Modeling of Arterial Stiffness using Variations of Pulse Transit Time

Aleksandar Peulić1, Natasa Milojevic2, Emil Jovanov3, Miloš Radović4, Igor Saveljić4, Nebojša Zdravković5 and Nenad Filipović4

  1. Technical Faculty, University of Kragujevac
    Svetog Save 65, 32000 Cacak, Serbia
  2. Intellectual Property Office
    Kneginje Ljubice 5, 11000 Belgrade, Serbia
  3. Electrical and Computer Engineering, University of Alabama
    Huntsville, AL 35899 USA
  4. Faculty of Engineering, University of Kragujevac
    Jovana Cvijica bb, 34000 Kragujevac, Serbia
  5. Medical Faculty, University of Kragujevac
    Svetozara Markovica 69, 34000 Kragujevac, Serbia


In this paper, a finite element (FE) modeling is used to model effects of the arterial stiffness on the different signal patterns of the pulse transit time (PTT). Several different breathing patterns of the three subjects are measured with PTT signal and corresponding finite element model of the straight elastic artery is applied. The computational fluid-structure model provides arterial elastic behavior and fitting procedure was applied in order to estimate Young’s module of stiffness of the artery. It was found that approximately same elastic Young’s module can be fitted for specific subject with different breathing patterns which validate this methodology for possible noninvasive determination of the arterial stiffness.

Key words

arterial stiffness, finite element modeling, microcontroller, pulse transit time

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Publication information

Volume 10, Issue 1 (Januar 2013)
Year of Publication: 2013
ISSN: 1820-0214 (Print) 2406-1018 (Online)
Publisher: ComSIS Consortium

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Peulić, A., Milojevic, N., Jovanov, E., Radović, M., Saveljić, I., Zdravković, N., Filipović, N.: Modeling of Arterial Stiffness using Variations of Pulse Transit Time. Computer Science and Information Systems, Vol. 10, No. 1, 547-565. (2013),